DNA Histamine
DNA Histamine
Histamine is regarded as a mediator of the neuro-immuno-endocrine system and is produced by many cell types, including basophils and mast cells. These cells are responsible for releasing endogenous histamine in response to immunological and nonimmunological stimuli. Histamine plays many key roles in the human body; it functions as a bronchoconstrictor in the lungs, a key mediator of wheal formation on the skin, a controller of gastric acid secretion, and a neurotransmitter in the brain. Another main source of histamines is food. The fresher the food, the lower the probability of histamine formation.
There are two main enzymes responsible for the degradation of histamine in the human body: Histamine N-Methyltransferase (HNMT) and Diamine Oxidase (DAO). Genetic polymorphisms in the genes encoding these enzymes can lead to an excess of histamine in the body, resulting in selective hypersensitivity to certain drugs, migraines, atopic dermatitis, and histamine intolerance, which is characterized by gastrointestinal, skin, and respiratory problems following the ingestion of histamine-rich foods.
There are many inconsistencies in the literature around the association of histamine with various other allergies, such as asthma and allergic rhinitis. This could be due to several reasons:
• Gender-related differences observed in the activities of the two histamine-degrading enzymes
• Interactions with unknown genetic polymorphisms
• Racial heterogeneity
• Various environmental factors that interact with an individual’s genetic architecture
See HERE a sample report.
How does it work?
A BloodSpot Analysis test kit will be sent to you by mail. All it requires is a few drops of blood from one of your fingers. Once completed, a booking can be made with the designated courier to collect the kit (with no additional charges), which will be delivered to the laboratory for testing.
How long will it take for my order to arrive?
All test kits are shipped and are expected to arrive within a few working days. The shipped test kits are considered concluded orders and are non-refundable any longer.
Average processing time:
18-21 days, after the test kits are returned to the lab. Return tests to the lab within 90 days of the order.
How do I take a sample?
All kits include straightforward instructions, allowing you to obtain a sample at home easily.
Are the tests reliable?
Yes! We use leading accredited laboratories to ensure that our testing is of the highest quality.
What will I receive after the test has been processed?
A report will then be generated with detailed information about the tested areas and recommended interventions. The report is presented in a patient-friendly manner so you can understand the possible issues and act upon the clearly formulated recommendations. You will be provided with a secure login on the lab platforms to view and download the results.
What happens after I receive the results?
You will be presented with the option to book an appointment with the doctor to further discuss the test results. The appointment will last about 30-60 minutes (includes the time the doctor needs to study the results), during which professional interpretation, further advice, and a possible therapeutic plan, based on your results, will be provided.
Privacy policy:
The DNA and the original sample material are destroyed after 3 months, so that there are no names or other identifiers on the samples. The samples are analysed only for the SNPs that are included in the tests at DNALife, and no other research or analyses are performed without separate permission from the patient. We do not give or sell the results to any third parties.
Important note:
Send us through the Contact Form (typed in the Comment field) your birthday, as well as your weight and height. This data is a requirement for the lab analysis.
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